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For a long time, autophagy was thought to be induced by starvation ( Bacterial and viral pathogen-associated molecular patterns (PAMPs) can trigger autophagy and induce professional immune cells to produce mitochondrial metabolites, including reactive oxygen species (ROS) and reactive nitrogen species (RNS) ( Dual-Role of Autophagy During Infection Autophagy degrades intracellular components or organelles to maintain physiological cell homeostasis